Ovarian stimulation with letrozole has been proposed to reduce multiple gestations while maintaining live birth rates. We enrolled couples with unexplained infertility in a multicenter ...

The drug letrozole results in higher birth rates in women with polycystic ovary syndrome (PCOS) than the current preferred infertility treatment drug, according to a nationwide American study.

Baseline E2 levels ranged from 3 pmol/L to 91 pmol/L with a mean of 25.7pmol/L. Only one of 54 (2%) patients had an E2 value ≥ 3 pmol/L after receiving letrozole, versus 20 of 54 (37%) patients after ...

The aromatase inhibitor letrozole, by suppressing estrogen production, might improve the outcome after the discontinuation of tamoxifen therapy. A total of 5187 women were enrolled (median follow ...

Letrozole is prescribed for certain types of breast cancer. It's a generic medication and is available as the brand-name drug Femara. It comes as an oral tablet. The cost of letrozole can vary ...

A letrozole pill once a week restored fertility in obese, infertile men and led to their partners giving birth to two full-term, healthy babies, according to a new study from Canada. A letrozole ...

A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes ...

This study evaluated the effects of palbociclib plus letrozole as neoadjuvant therapy for postmenopausal women with estrogen receptor (ER)-positive breast cancer who were being treated with the ...

“Letrozole ameliorated MCD- and CCl4-induced liver fibrosis by suppressing the Yap-Ctgf pathway by partially modifying the expressions of Hsd17b13 and Cyp26a1, which reduced retinoic acid level ...

NCIC CTG MA17 [1] was a phase 3, randomized, double-blinded, placebo-controlled trial investigating extended letrozole in women with estrogen receptor positive (ER+) breast cancer who were ...

On average, the men had been infertile for nearly three years. The men received a 2.5-milligram letrozole pill every week. Their follow-up ranged from two to 21 months. One man did not tolerate ...