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Intermittent food intake activates a 'GPS gene' in liver cells, thus completing the development of the liver after birth
Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte position map. They also found that what triggers ...
EurekAlert!26d
Identification of the mTOR pathway as a key target for diabetic nephropathy treatment
It examines the impact of mTOR on podocytes ... developmental biology, gene regulation and epigenetics, cancer biology, immunity and infection, neuroscience, disease-specific animal models ...
Medical Xpress19d
Scientists identify neural mechanism of leptin resistance in obesity—and how to reverse it
"With this as a starting point, we found that mTOR is hyperactive in specific brain ... on neurons in the hypothalamus that express a gene known as POMC. These neurons are known to mediate ...
News Medical26d
New insights into mTOR pathway offer hope for diabetic nephropathy treatment
It examines the impact of mTOR on podocytes, glomerular mesangial cells, renal tubular epithelial cells, and glomerular endothelial cells—each playing a crucial role in kidney function.
EurekAlert!17d
RNA cargo in motion: The exosomal connection to head and neck cancers
Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).
GEN19d
Rapamycin Restores Leptin Sensitivity and Leads to Fat Loss in Obese Mice
“With this as a starting point, we found that mTOR is hyperactive in specific brain ... on neurons in the hypothalamus that express a gene known as POMC. These neurons are known to mediate ...
WebMD29d
Stage IV Breast Cancer Treatment Options
mTOR inhibitors. Everolimus (Afinitor ... and can be used to treat certain types of breast cancer with a PIK3CA gene mutation. Antibody-drug conjugates. This therapy consists of a monoclonal ...