In particular, there is an area near the 5' end of the molecule that is known as the untranslated region (UTR) or leader sequence. This portion of mRNA is located between the first nucleotide that ...

have analyzed global changes in mRNA length in a murine model of atherosclerosis progression. They observed variations in the 5'UTR, 3'UTR, and coding regions of mRNAs, which become shorter as ...

A typical bacterial mRNA transcript controlled by a riboregulatory element such as a riboswitch is composed of three sections: the 5' untranslated region (5' UTR), the protein-coding region ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the ...

We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a transcription factor did not change how much of the transcription factor protein was expressed but determined the location ...

Feb. 14—A bill that would ban the use of mRNA vaccines, including for Covid-19, is on its way to the House floor after passing out of committee in a party-line vote Wednesday. Sponsored by Rep.

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...