At least 51 people were killed and more than 200 others injured by Israeli fire as they waited for aid trucks to arrive in Khan Younis in southern Gaza early Tuesday morning, the Palestinian Ministry of Health said.

An Israeli official said that "there's never a 100 percent guarantee," but "a nuclear disaster" should "not happen."

Blasts rang out across a swath of the Middle Eastern republic’s territory, targeting Iran’s nuclear capabilities, military leadership and scientists.

Mohammad-Reza Zafarghandi said in an update that an Israeli strike on Sunday on Quds Square in northern Tehran injured 59 civilians and killed 12 people, including a pregnant woman. That attack also ruptured a main water pipeline.

UK military ‘could be used’ to defend Israel as IDF claims to have hit Isfahan nuclear facility - Six reportedly killed in strike on building in Bat Yam as Israel and Iran trade missile strikes

Follow live updates as Iran retaliates after Israel strikes nuclear facilities. Stay informed with real-time news and developments.

Israel had a plan to assassinate Iranian Supreme Leader Ayatollah Ali Khamenei, but President Trump vetoed the operation, according to reports.

Dozens of others were injured overnight across Israel, the authorities said. Israel was striking military sites in Iran and the four-day-old conflict showed no sign of slowing.