We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP (bone morphogenetic protein) and receptor tyrosine kinases ...
Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.
Some examples of inhibitors are listed in Table 1. Table 1: Examples of Ras-Raf-MEK-ERK signaling inhibitors. Dysregulated Wnt signaling is linked to numerous cancers including; leukemia, melanoma, ...
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Study delves into the role of SOX9 in hypospadias developmentHypospadias is a widespread congenital disorder, characterized by an abnormal placement of the urethral opening, impacting as ...
Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...
A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common ...
Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...
Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...
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