Future research will therefore demonstrate how important the Wnt–β-catenin signalling pathway is for the self-renewal of cancer stem cells. The past two decades have seen a number of cases in ...

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...

A recent study has unveiled the critical roles of two transcription factors, MAFB and CEBPA, in the development of ...

A recent study has uncovered the pivotal role of the transcription factor SOX9 in the development of hypospadias, a common congenital condition that affects male children.

A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...

Mechanistically, transcriptome analysis revealed that IFN-γ reversed most iMEK-induced global transcriptomic changes, partly by regulating Wnt/β-catenin signaling and the transcription factor Myc.

ST316, a β-catenin/BCL9 antagonist, demonstrated safety, target engagement, and early antitumor activity in advanced solid ...

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...

Wnt signaling pathway The Wnt signaling pathway is a conserved network that regulates cell proliferation, differentiation, ...