Preclinical data has showing compelling findings for HT-KIT among patients with rare and aggressive KIT-driven cancers, ...

Most advanced gastrointestinal stromal tumors (GISTs) start with cancer-causing cell changes, or mutations, in specific genes. Changes in proteins called KIT and PDGFRA most commonly cause this ...

GISTs are a rare type of cancer that develops in the digestive tract’s connective tissue, specifically from cells that help regulate muscle contractions. GISTs are primarily driven by genetic ...

A tumour means a lump or growth in the body, which may or may not be cancer. Most GISTs develop in the digestive system. But some start outside the digestive system in nearby areas such as the: Some ...

Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...

A gastrointestinal stromal tumor (GIST) is a cancerous tumor that grows in the digestive tract. Surgery can help remove the entire tumor. There are several procedures, including laparoscopy or ...

If you have advanced gastrointestinal stromal tumor (GIST), you may not know anyone else with the disease. This may leave you with a lot of questions about what life will be like with this rare ...

Huntsman Cancer Institute’s Sarcoma Service has a specialist team that treats soft-tissue sarcomas that form in the abdomen. Here are some soft-tissue sarcomas of the abdomen: Gastrointestinal stromal ...

Multivariate analysis by Cox proportional hazards regression (Forward LR) model indicated that tumor size, mitotic rate, and risk grade were independent risk factors to OS for GISTs, and that ...

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these ...