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Natural enzymes are remarkable molecular machines that enable all sorts of essential biochemical reactions. For decades, ...
Microorganisms generate all sorts of materials that could serve as potential agents for combating bacteria and fungi. An ...
Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, ...
Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...
Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical ...
Compared with traditional chemical synthesis, enzyme catalysis is more environmentally friendly and efficient. It has been widely used in the industrial production of functional molecules such as ...
There are many different PLP enzymes that catalyze a variety of reactions, so this sort of dual-catalyst approach could open up many other types of synthetically useful reactions, he says.
Once they made an enzyme with boronic acid at its reactive centre, they could use directed evolution to increase its efficiency, resulting in faster catalysis. 'Furthermore, by placing the boronic ...
Reactions that can combine more than two molecular pieces in one go are a powerful way to build complexity quickly and save on costly isolation and purification. But the choreography for such a ...