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DNA methylation refers to the addition of a methyl (CH3) group to the DNA strand itself, often to the fifth carbon atom of a cytosine ring. This conversion of cytosine bases to 5-methylcytosine is ...
Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...
DNA methylation is one of the ways in which cells organize distinct identities despite inheriting the same genome.
A new study published in Nature Mental Health provides evidence that early-life adversity can leave lasting biological imprints that help explain why some children develop depression later in life, ...
In order for the DNA methylation pattern to be altered, there must be both active DNA methylation and demethylation in the neuronal genome. However, no enzymes are known to cleave the methyl group ...
DNA methylation and gene expression in children Date: April 4, 2022 Source: Barcelona Institute for Global Health (ISGlobal) Summary: A new study identifies associations between DNA methylation ...
DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...
View Full Profile. Learn about our Editorial Policies. DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in ...
Study: Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use. Image Credit: Juan Gaertner / Shutterstock With an increasing number of states in the ...
A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D ...
DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...
Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...