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If a chemical is soluble in water, ... Colorful assortment of permanent markers. Water. 70 percent isopropyl alcohol (aka rubbing alcohol) Medicine dropper. White T-shirt that can be dyed.
Extra: In this activity you used water-soluble markers in combination with water as a solvent. You can test permanent markers using isopropyl rubbing alcohol as a solvent.
IDEAS FOR THE INFORMAL SETTING. As an alternative, this activity can be done on a smaller scale with students creating individual watersheds using paper bags and water-soluble markers.