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for many viruses the fusion event occurs at the plasma membrane of the target cell and, in these cases, extra proteins in the viral envelope might be involved in assisting the fusion process.
Viral membrane fusion to the host endosomal membrane is an essential step to successful infection. The rate and efficiency at which fusion occurs is determined by multiple independent variables and is ...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is critical for membrane fusion and eventual viral infection. Enveloped viruses use highly specific protein machinery ...
Despite its isolation three decades ago, Ebola virus continues to cause periodic outbreaks of severe hemorrhagic fever in humans, and the closely related Marburg virus is responsible for a recent ...
To study how HA can facilitate the fusion between viral membrane and host endosome membrane, Wong and colleagues let HA interacted with exosomes, a lipid bilayer cargo that mimics endosome.
In this way, membrane fusion provides the molecular basis for all our thoughts. Another example is viral infection. Many viruses, such as the influenza or the HIV virus, hide behind a membrane ...
"HB27 probably inhibits SARS-CoV-2 infection at multiple steps during the viral entry process." This is the first antibody reported to be capable of preventing membrane fusion by a coronavirus.
"It's the first time a role for membrane fusion has been described for this complex and it's a breakthrough in how we think ...
Diabetes, heart disease, high blood pressure, cancer, and viral infections also depend highly on membrane fusion and could eventually be treated by intervening in this process, Dr. Rizo-Rey said.
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