homotypic fusion, where two endosomes fuse rapidly to form a single vesicle, and heterotypic fusion, in which lysosomes ...

Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other ...

and catalyze vesicle fusion. While the biological roles of these membrane trafficking complexes have been established, our understanding of how they are assembled is still in its early stages. Our ...

Finally, a core layer of proteins interact to bring vesicle membranes in exceedingly close apposition with their cognate target membranes, thereby driving membrane fusion. Each of these processes ...

In plants and fungi, lysosomes are called acidic vacuoles. Lysosomes are formed by the fusion of vesicles that have budded off from the trans-Golgi. The sorting system recognizes address sequences ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...