Utrophin increase in muscle cells normalises cell function ... And these fragments surprisingly take on new functions in the regulation of other genes,’ explains co-author Christopher Dooley. The Max ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window LOS ANGELES -- The investigative utrophin modulator ezutromid showed promise in treating Duchenne muscular dystrophy ...

SUMMIT HIGHLIGHTS UTROPHIN MODULATION AS A POTENTIAL UNIVERSAL TREATMENT OPTION IN DMD AT 15th ACTION DUCHENNE INTERNATIONAL CONFERENCE New Preclinical Data Show Utrophin`s Positive Effect on ...

Summit Therapeutics reported 24-week data showing its Duchenne muscular dystrophy drug ezutromid boosted utrophin levels and decreased muscle damage in a phase 2 trial. DMD is caused by mutations ...

Summit retains commercialization rights to the pipeline in all other countries. “Summit's utrophin modulation technology represents a potentially promising approach to treat DMD, which may ...

Professor Kay Davies said trials of a drug to increase levels of the protein utrophin, to maintain the muscles, would start later this year. She told Oxfordshire Science Festival it could help ...

Moreover, Summit is eligible to receive development and regulatory milestones related to its next-generation utrophin modulators. The company is also entitled to additional fees, milestones ...