Although tumor-induced osteomalacia is a rare disorder, we propose that systematic analysis of somatostatin-receptor expression has relevance to tumor-derived phosphatonin secretion.

A small cohort of adults with tumor-induced osteomalacia experienced improvements in phosphate and skeletal metabolism, physical functioning and quality of life after 144 weeks of treatment with ...

Tumor-induced osteomalacia is a rare disease in which small tumors produce fibroblast growth factor 23 (FGF23), leading to phosphate wasting and impaired vitamin D synthesis.

Tumor-induced osteomalacia is a rare condition characterized by tumor-related renal phosphate wasting and abnormal vitamin D metabolism, which results in progressively worsening weakness, bone ...

Tumor-induced osteomalacia (TIO) is a rare disease characterized by slow-growing tumors that release excess levels of FGF23, which suppresses renal tubular phosphate reabsorption and the renal ...

The global tumor-induced osteomalacia market size was USD 118.25 million in 2024, estimated at USD 121.12 million in 2025, and is expected to reach around USD 153.00 million by 2034, expanding at ...

Increased phosphate levels led to improvements in osteomalacia. The tumors associated with TIO release a peptide hormone-like substance known as FGF23 that lowers phosphate levels.

Oncogenic osteomalacia is a rare syndrome that is usually driven by small, mesenchymal tumors that express phosphatonins, proteins that decrease the abundance of sodium–phosphate cotransporters ...

Clinical Characteristics of Malignant Phosphaturic Mesenchymal Tumor Causing Tumor-Induced Osteomalacia Journal: Journal of Clinical Endocrinology & Metabolism Published: 2023-11-26 DOI: ...

Healthcare Resource Use Associated With Tumor-Induced Osteomalacia: A Literature Review Journal: Journal of Clinical Endocrinology & Metabolism Published: 2024-06-25 DOI: 10.1210/clinem/dgae431 ...

Chest, ankle, and hip pain are presented in a previously healthy 32-year-old man whose unusual, persistent musculoskeletal symptoms pointed to tumor-induced osteomalacia. How is this diagnosis made?