Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors found in the pontine region of the brainstem.

The tumor cells of highly aggressive glioblastomas grow into the brain like a mycelium. This invasion is promoted by the nerve cells of the brain itself as they form cell-cell contacts with the ...

The team discovered that the tumor specifically reprograms the neurons for its own benefit. In mice, blocking nerve function inhibited cancer growth and increased the sensitivity of tumor cells to ...