Here we present SignalP version 4.0, which we designed to discriminate between signal peptides and transmembrane regions. In training SignalP 4.0, we used two kinds of negative data: the first ...

The twin-arginine translocation (Tat) pathway of bacteria and plant chloroplasts mediates the transmembrane transport of folded proteins, which harbour signal sequences with a conserved twin ...

Human signal peptide peptidase may represent another family of aspartic proteases that promote ... Weihofen et al. identified human SPP as a polytopic membrane protein with sequence motifs ...

Claudins contain four transmembrane-spanning domains with peptide loops on the membrane's exterior. Combined, those loops form three-dimensional structures, or epitopes, targeted by diagnostic or ...

TMEM63B, a transmembrane protein expressed in subfornical organ (SFO) neurons, functions as a hyperosmolar sensor that detects increased blood osmolality and triggers thirst in mammals.

SecA accepts the unfolded proteins and threads them through the transmembrane channel (PCC). 75 The Tat system, dedicated for transport of folded proteins, consists of three membrane-integrated ...

Nachrichten » Versameb AG Announces Grant of First Patent in China for "Signal Peptide with Heterologous Protein" Push Mitteilungen. PR Newswire. 20.03.2025 09:36 Uhr. 513 Leser.

G-protein coupled receptors (GPCRs) play pivotal roles in signaling pathways and are the most common membrane proteins. Implicated in many diseases, they are an attractive therapeutic target.