Based on the information presented here, the authors suggest that routine use of topical neomycin postoperatively for closed wounds should be strongly discouraged. Furthermore, given the notable ...

Neomycin is the most commonly used topical antibiotic in the United States and in many European countries (Marks et al., 2002). It is available in both prescription and over-the-counter preparations.

The small amounts of neomycin required for topical use on the skin, its poor absorption from the lumen of the intestinal tract, the broad spectrum of its antibacterial action, the relative ...

Consider cross-hypersensitivity to other aminoglycosides, and the possibility that patients who become sensitized to topical neomycin may also be sensitive to other topical and/or systemic ...