In the first part of this series, we explored how early genetic screening and gene therapy transform the lives of newborns ...

In the past, obesity often was considered a sign of weak willpower and a lack of self-restraint. But the discovery of the obese gene (ob gene) in 1994 by Jeffrey Friedman, a Howard Hughes Medical ...

The product of the ob gene, leptin is a circulating hormone produced by white adipose tissue that has potent effects on feeding behavior, thermogenesis and neuroendocrine responses. Leptin ...

The personalized CRISPR treatment could be the future of gene therapy, but hurdles remain before everyone has access.

identifying the protein responsible for obesity in genetically obese mice (six years before identification of the ob gene), and exploration of gut factors regulating metabolism, such as the ...

A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops. Researchers discovered ...