and “rheumatologists feel a bit more comfortable with [neutropenia] as a side effect rather than [tuberculosis] coming out through TNF-α inhibition. Those side effects do not compare ...

55 11 3061 7457 Fax: +55 11 3081 7190 mahong@usp.br Establishing that TNF-α plays an important role in the pathogenesis of several immune-mediated inflammatory diseases led to the development of ...

However, on infiltrating the sAH liver, these neutrophils are stimulated by the inflammatory environment, including mediators such as TNF-α and IL-1β, to produce high levels of IL-8. This IL-8 ...

The fully funded study is expected to evaluate TNF-α levels in patients receiving GLP-1 agonist Wegovy or Ozempic who show signals for increased inflammation associated with sarcopenia.

Hypoxia-ischemia induces an inflammatory response in the immature central nervous system that may be important for development of brain injury. Recent data implicate that chemoattractant cytokines ...

The study suggests that extracellular ADA2 regulates myeloid cell polarization, TNF-α secretion, neutrophil activation, and IFN-β secretion by epithelial cells. The intracellular role of ADA2 in ...