The neuromuscular junction consists of a motor nerve terminus, the neurotransmitter acetylcholine, and the postsynaptic muscle endplate. (Figure 1.) The impulse of an action potential causes the ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

Expanded research operations led by Drs. Joseph Moskal and Jeffrey Burgdorf of Northwestern University, pioneers of the “stinel” class of NMDA receptor modulators Research focused on advancing ...

Clathrin light chain (CLC) subunits in vertebrates are encoded by paralogous genes CLTA and CLTB, and both gene products are alternatively spliced in neurons. To understand how this CLC diversity ...

Scientists reveal how toxic protein pores in brain cells may explain Parkinson’s progression at molecular level.

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...