The result is an older, gaunter appearance. Some potential drug interactions to be aware of: Insulin or sulfonylureas (glipizide, glyburide, tolbutamide) may cause hypoglycemia (low blood sugar ...

Glipizide/metformin HCl; 2.5mg/250mg, 2.5mg/500mg, 5mg/500mg; tabs. Adjunct to diet and exercise in type 2 diabetes, as initial therapy or as second-line therapy when response to a sulfonylurea or ...

The longer-acting agents (e.g. chlorpropamide, glyburide [glibenclamide], and sustained-release glipizide) are more likely to cause hypoglycemia than glipizide, glimepiride, and gliclazide.

Sulfonylureas close these channels and restore insulin release, and have been successfully used to replace insulin treatment for patients with Kir6.2 mutations. Now, Hattersley et al. describe the ...

Whether thiazolidinediones should be used to treat patients with type 2 diabetes mellitus is controversial, as studies on the cardiovascular effects of these drugs have produced conflicting results.

Data Synthesis: Studies of glyburide and glipizide have found little or no transfer of these drugs across the placenta, whereas metformin and rosiglitazone cross readily. Animal studies have found ...