Researchers from the US have shown that combination therapy with sitagliptin and metformin results in a substantial and additive glycemic improvement in patients with type 2 diabetes. Sitagliptin ...

Sitagliptin, metformin (as HCl) ext-rel; 50mg/500mg, 50mg/1000mg, 100mg/1000mg; tabs. Individualize. Swallow whole. Take once daily with a meal, preferably in the evening. Not currently treated ...

Sitagliptin (Januvia™) is a new oral agent ... 1 Intent-to-treat population using last observation on study prior to metformin rescue therapy. *Least square means adjusted for prior ...

The latest verdict – in a federal appeals court – has upheld the validity of a key patent on sitagliptin, the active ingredient in Januvia, as well as metformin combinations Janumet and ...

The study group consisted of stratum 1 (glimepiride alone, n = 212) and stratum 2 (glimepiride plus metformin, n = 229). Patients in each stratum were randomized to sitagliptin 100 mg once daily ...

The combination of sitagliptin and metformin provided a more than additive effect on native GLP-1 concentrations. This combination may benefit patients with Type 2 diabetes through substantial ...