Sitagliptin dose-dependently protects rat kidneys from acute IR injury via upregulation of serum GLP-1 and GLP-1 receptor expression in kidneys. ... etiologies, mechanisms, classification, ...

Janumet™ (MK-0431A) combines two OADs with complementary mechanisms of action to improve glycemic control, sitagliptin and metformin. The tablet was designed in order to be bioequivalent to ...

Sitagliptin lowers glucagon and improves glucose tolerance in prediabetic obese SHROB rats. Experimental Biology and Medicine , 2011; 236 (3): 309-314 DOI: 10.1258/ebm.2010.010161 Cite This Page : ...

The sitagliptin group also had a decreased risk for use of a mechanical ventilator during hospitalization (HR = 0.27; 95% CI, 0.11-0.62) and ICU admission (HR = 0.51; 95% CI, 0.27-0.95) compared ...

For the study, patients received sitagliptin 25 mg daily or glipizide initiated with 2.5 mg daily and titrated up to a potential maximum dose of 10 mg twice daily or down to avoid hypoglycemia.

(HealthDay)—The dipeptidyl peptidase-4 (DPP-4) inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion, according to a study published online June 14 in ...

Over a mean follow-up of 2.9 years, there were no significant differences between sitagliptin versus placebo for the risk of hospitalization for heart failure (3.1% versus 3.1%, respectively) or ...