to achieve plasma concentrations of sitagliptin similar to those in patients with normal renal function, a dosage adjustment is recommended for patients with moderate renal insufficiency (50 mg ...

Janumet™ (MK-0431A) combines two OADs with complementary mechanisms of action to improve glycemic control, sitagliptin and metformin. The tablet was designed in order to be bioequivalent to ...

A total of 1,091 patients with type 2 diabetes and HbA 1c levels of 7.5–11.0% were randomly assigned to receive combination therapy with daily sitagliptin (100 mg) and metformin (either 1,000 mg ...

For diabetes: • Sitagliptin: Film-coated tablet (25 mg, 50 mg, 100 mg). • Sitagliptin (as hydrochloride) + Metformin Hydrochloride: Film-coated tablet (50 mg/1 g, 50 mg/850 mg).