RTKs can activate Ras, a protein that is tethered to the plasma membrane, by causing it to bind GTP. Once activated, Ras can do a variety of things. In this example, it activates an enzymatic ...

And still, something feels off. How about giving the ground some texture, too? A pathway can easily bring a dreamy, almost fairy-tale-like feel to any backyard. But as you probably already know ...

Consequently, new therapeutic strategies are required. Pippa Newell and colleagues found that molecular alterations of the Ras pathway are common in HCC and that the multikinase inhibitor ...