Progressive rounds of octamer ligation enable sequencing of every 5 th base (e.g., bases 5, 10, 15, 20). Upon completing several such cycles, the extended primer is denatured to reset the system.

SEATTLE--(BUSINESS WIRE)--Phase Genomics, Inc., a global innovator for industry-leading genomic solutions, today announced the presentation of new data from the proximity ligation sequencing-based ...

Their proximity ligation technology couples well with Element’s improvements in sequencing accuracy, lower optical duplication rate and consistency of data, across a range of applications ...

Jay Shendure, Greg Porreca and colleagues working in George Church’s laboratory described a workflow based on ePCR and sequencing by ligation to sequence a tryptophan-deficient derivative of the ...