A new research paper titled "Mapping the core senescence phenotype of primary human colon fibroblasts" has been published in Aging. Advanced age is the largest risk factor for many diseases and ...

Exogenous expression of the ras oncogene triggers senescence in human fibroblasts. Staining with DAPI reveals the gradual appearance of senescence-associated heterochromatin foci, transcriptionally ...

The research focuses on cellular senescence, a process where cells ... advanced sequencing and bioinformatics analyses on ...

The Senescence Accelerated Mouse-Prone 8 (SAMP8) is a naturally occuring mouse line that displays a phenotype of accelerated aging. While maintaining an inbred AKR/J line in the early 1970's, ...