“[...] despite the impact of aging on colon health and colon cancer, an atlas of the SASP produced by colon fibroblasts has not been established.” Advanced age is ...

“Novel senomorphic and senolytic agents can be evaluated in this model as they are identified.” Idiopathic pulmonary fibrosis (IPF) is an age-related disease with poor prognosis and limited ...

According to the latest statistics from the National Cancer Institute, more than 60% of cancer patients are 65 or older and the median age at diagnosis is 66. In fact, age is the largest risk factor ...

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Human senescent fibroblasts ...

Mechanical damage to the cell membrane was previously believed to trigger two simple cellular outcomes: recovery or death. However, a new study led by the Okinawa Institute of Science and Technology ...

When cells age and stop dividing, that’s called cellular senescence. In the short term, senescence protects against DNA damage and tumor formation. Then the immune system eliminates the senescent ...

Researchers discovered that a protein called AP2A1 acts as a master switch controlling whether cells behave young or old When ...

Exogenous expression of the ras oncogene triggers senescence in human fibroblasts. Staining with DAPI reveals the gradual appearance of senescence-associated heterochromatin foci, transcriptionally ...

For the first time in the world, a Korean research team has discovered how aging in one part of the body can spread to another via the bloodstream. The discovery offers new insights into how aging ...

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation ...