However, the minimal number of SNARE complexes needed for membrane fusion is not known. Here we show unambiguously that one SNARE complex is sufficient for membrane fusion. We performed controlled ...

It does that by talking to the membrane fusion protein." More information: Chanwoo Lee et al, Exocyst stimulates multiple ...

Accepter SNARE proteins then form, allowing fusion with another vesicle membrane. How this mechanistically ... physiological model is that a tethering complex (termed HOPS) is interacting with ...

Fusion has been thought to occur via the spontaneous zipper-like assembly of the SNARE protein complex, which may distort and pucker the membrane, physically forcing the lipids in the membrane ...

According to a popular model, membrane fusion occurs when soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins on one membrane form a complex with SNARE proteins on ...

2. Chaperone-assisted assembly of SNARE complexes and its roles in metabolism and diabetes. Intracellular vesicle fusion is catalyzed by a class of membrane-bound proteins known as soluble ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

SNAP-25 is one component of the SNARE core complex which also includes Syntaxin ... with syntaxin 1 and is thought to help restrict fusion of vesicles to specific sites of the plasma membrane.