Here, authors present apical-out nasal organoids using a biochemically defined hydrogel system, revealing that matrix metalloproteinases are required for normal epithelial development.

Since this work targets the immune system and not the specific virus, the models are expected to impact many respiratory infections, including COVID-19 "The immune system is a complex, interactive ...

Parts of the model represent different parts of the respiratory system as shown here. The model, which is air tight, represents the thorax, and air is only able to enter via the glass tube which ...

The researchers incorporated this understanding of the impact of environmental factors on droplet spread into a new mathematical model that can be used to predict the early spread of respiratory ...

The respiratory system is responsible for the exchange of carbon dioxide and oxygen in the human body. This system also helps remove metabolic waste products and keep pH levels in check.

Results from the VirTus Respiratory Research Ltd Human Rhinovirus Challenge Model Used to Advance Altesa BioSciences’ Lead Medicine into Advanced Clinical Trials Study conducted by VirTus ...

Thirteen factors were identified as potential predictors of acute respiratory distress syndrome. With these factors, the model had positive predictive and discriminatory ability in sepsis patients.

At VirTus Respiratory Research Ltd, the rhinovirus challenge model is used to generate early signals of clinical efficacy in a tightly controlled, reproducible setting. By exposing volunteers to ...