The aldosterone-renin ratio (ARR) has gained popularity as a screening test for primary hyperaldosteronism, a probably underdiagnosed cause of hypertension. However, studies have yielded varying ...

The typical presentation of patients with Liddle syndrome includes early-onset severe hypertension, hypokalemia, metabolic alkalosis in the setting of low plasma renin and aldosterone, low rates ...

A high sodium intake inhibits the renoprotective effect of blockade of the renin–angiotensin–aldosterone system (RAAS). Vogt et al. investigated the combined effects of a low-sodium diet and ...

The two primary mechanisms — considered “neurohormonal” responses — are activation of the sympathetic nervous system (SNS) and activation of the renin-angiotensin-aldosterone system (RAAS).