Our data suggest that EGFR tyrosine kinase mutations can be used to identify the subgroup of patients with non–small-cell lung cancer in whom this growth factor receptor may be essential to ...

Bruton's tyrosine kinase (BTK), an essential component of B-cell–receptor signaling, mediates interactions with the tumor microenvironment and promotes the survival and proliferation of CLL cells.

During the past few years, the demand of receptor tyrosine kinase inhibitors is increasing exponentially as several studies have demonstrated a crucial role of these receptors in the regulation of ...

Mesenchymal epithelial transition (MET) proto-oncogene receptor tyrosine kinase (RTK) is a cell surface receptor selective for hepatocyte growth factor (HGF), and is involved in embryogenesis ...

Fibroblast growth factor receptors are one of the major receptors tyrosine kinase, which is expressed over the normal cells and mutation in this receptor is associated with the initiation of ...