Pegula, the world No. 3, lost in the first round at a major tournament for the first time since the French Open in 2020.

Buffalo native Jessica Pegula is headed home after a stunning first-round 6-2, 6-3 defeat by No. 116 ranked Elisabetta Cocciaretto at Wimbledon.

Italy's Elisabetta Cocciaretto registered the biggest win of her career when she knocked out American Jessica Pegula, the No. 3 seed, in less than an hour at Wimbledon.