Nat Clin Pract Neurol. 2007;3(4):221-228. Another practical -- although somewhat banal -- advantage of ramelteon over melatonin is the fact that melatonin has not yet obtained regulatory approval ...

Consequently, there has been an active search for patentable melatonin receptor ligands in recent years. Ramelteon, an agonist that acts solely on melatonin MT 1 and MT 2 receptors, is of ...