Our knowledge of RNA splicing is quite new. Nonetheless, because nearly all eukaryotes have introns and share mechanisms of RNA splicing, splicing itself must be quite ancient. Proponents of the ...

RNA splicing is a post-transcriptional modification process that ... thereby expanding the functional repertoire of the genome. This mechanism is often referred to as a "space-saving" or "economical" ...

The mechanism for enhancing splicing at this RNA site also was previously unknown. The researchers discovered that a protein called SNRPA1, which plays a role in normal alternative splicing as ...

Alternative splicing, a complex and prevalent mechanism in the brain and body ... Lead author Atsushi Takata and colleagues started with RNA sequencing data derived from the brain tissue of ...

Surprisingly, this shift did not significantly change global gene activity, but it altered how certain RNA transcripts were processed—a mechanism known as alternative splicing, which enables ...

Ahn’s study, “SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 ... so we need to achieve a better understanding of the underlying molecular mechanisms of this deadly tumor ...

In this study, Shulman and his colleagues investigated a molecular mechanism called RNA splicing that is involved in the production of mature RNA molecules necessary to produce working proteins. They ...

Alternative splicing (AS) – a mechanism that regulates proteome diversity through single RNA-splicing, generates alternative mRNAs that encode distinct protein isoforms. This pathway can be ...

Alternative splicing, a complex and prevalent mechanism in the brain and body ... Lead author Atsushi Takata and colleagues started with RNA sequencing data derived from the brain tissue of ...