The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene.

Plants survive cold by adjusting at cellular level. Scientists discovered that the PORCUPINE protein helps plants adapt to ...

Fungal tRNA Splicing as a Paradigm of RNA Repair – Intron-containing tRNAs are widespread ... (ii) developing a kinetic mechanism for the healing and sealing steps; (iii) highlighting distinctive ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Specific RNA Sequences Are Required for Regulation ... Chen, M. & Manley, J. L. Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches.

Alternative splicing (AS) of pre-mRNA plays a crucial role in tissue-specific gene regulation, with disease implications due to splicing defects. Predicting and manipulating AS can therefore uncover ...

DNA begets RNA begets protein. Now, thanks to a wave of new bioinformatics databases, techniques, and studies, alternative splicing has emerged as not only pervasive, but perhaps as a central ...

A study reveals how cancer disrupts RNA splicing and presents a potential therapy using antisense oligonucleotides to target ...

CUGexp RNA forms based-paired structures that bind ... to identify previously unknown roles for coordinated alternative splicing and additional post-transcriptional regulatory mechanisms during ...

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different ...