However, its role as a nucleobase in RNA was not established until the 1940s, when the structure of DNA and RNA was elucidated. The discovery of uracil and its pairing with adenine in RNA was a ...

But real lightning would have struck infrequently—and mostly in open ocean, where organic compounds would have quickly ...

The primary function of guanine is to store and transmit genetic information in DNA and RNA. In DNA, guanine is always paired with cytosine, and the sequence of these base pairs determines the genetic ...

The key to this is the modification of the original ligand with a reactive "handle" that allows it to react with a nucleobase at the RNA binding site. This was first demonstrated in vitro and in ...

NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-56261-7 Cite This Page : ...

More information: Yuki Kagaya et al, NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation, Nature Communications (2025). DOI ...

Reference: Kagaya Y, Zhang Z, Ibtehaz N, et al. NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation. Nat Commun. 2025;16(1):881. doi: ...

They encode our bodies’ makeup, functions, and inheritance. RNA, which transmits the instructions contained in genes to the protein-making factories in cells, uses an additional nucleobase, which is ...

Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each consist of a nucleobase ... secondary structures of DNA or RNA that play key roles in numerous biological ...