New pyrimidine compounds may lead to improved treatments for childhood brain cancer. ScienceDaily. Retrieved June 3, 2025 from www.sciencedaily.com / releases / 2010 / 04 / 100406093512.htm.

A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, ... New pyrimidine compounds may lead to improved treatments for childhood brain cancer ...

The quinazolinone and pyridol-pyrimidine classes of p38 MAP kinase inhibitors have a previously unseen degree of specificity for p38 over other MAP kinases. Comparison of the crystal structures of ...

Pyrimidines are a class of aromatic heterocyclic organic compounds that form the building blocks of nucleic acids, the genetic material of all living organisms.They are essential components of DNA and ...

Previous research has identified ribose aminooxazoline as a potential intermediate in the prebiotic synthesis of the pyrimidine nucleotides with remarkable properties. It crystallizes ...

Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with ...

Pyrimidine compounds acting as ubiquitin carboxyl-terminal hydrolase 1 (USP1) inhibitors and reported to be useful for the treatment of cancer have been disclosed in a recent Asieris Pharmaceuticals ...

In particular, the new study has identified mutations in the SLC28A1 gene, which could affect the synthesis of the hCNT1 protein and therefore, alter the pyrimidine metabolism (organic compounds ...

Shanghai Visonpharma Co. Ltd. has identified pyridine[4,3-d]pyrimidine compounds acting as Toll-Like receptor 7 (TLR7) and TLR8 agonists reported to be useful for the treatment of cancer and viral ...

A research team has described the first case of a patient affected by dysfunctions in a nucleoside transporter of the SLC28 gene family, which brings a set of genes which were not related to human ...

A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and causing cancer cell death in medulloblastoma.