A large-scale genome study uncovered IL31 as a key genetic contributor to prurigo nodularis, linking it to immune-regulatory ...

Prurigo nodularis is an inflammatory condition related to the skin’s nerve and immune cells, so there isn’t much you can do to prevent it. If you have PN, you can take steps to reduce flares ...

The antibody received the US FDA’s approval in August 2024 for adults with prurigo nodularis. ... (Relfydess) for treating moderate-to-severe frown lines and crow’s feet.

The encouraging long-term efficacy and safety associated with nemolizumab (IL-31 inhibitor) in prurigo nodularis was supported by a second set of data showing long-term benefit in atopic dermatitis.

For adult patients living with prurigo nodularis, dupilumab (Dupixent) was shown to significantly improve their skin lesions, quality of life (QOL), and itching, reports a new study in Anais ...

Prurigo nodularis is a chronic, debilitating, and severely pruritic neuroimmunologic skin disease. Nemolizumab, an interleukin-31 receptor alpha antagonist, down-regulates key pathways in the patho ...

The application for the prurigo nodularis indication includes data from two phase 3 trials: OLYMPIA 2 (ClinicalTrials.gov Identifier: NCT04501679) and OLYMPIA 1 (ClinicalTrials.gov Identifier ...

Results from OLYMPIA 1 provide further support for nemolizumab as a potential first-in-class prurigo nodularis treatment; in another study, a JAK inhibitor was beneficial in patients with PN.

Galderma has received filing acceptances for nemolizumab for the treatment of patients with prurigo nodularis and for adolescents and adults with moderate-to-severe atopic dermatitis in Australia ...

Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized by intense itch and thickened red bumps on the arms, legs and trunk. 1 Due to the result of persistent, intense ...

The Food and Drug Administration (FDA) has approved Nemluvio ® (nemolizumab-ilto) for the treatment of adults with prurigo nodularis.. Interleukin (IL)-31 is a neuroimmune cytokine that is ...