terminus, the team called the extensions CAT tails. Together, the evidence was convincing. “What all of this was saying was that we were getting a totally unprecedented mechanism for ribosome-mediated ...

Table 1 shows the N-terminal sequences of proteins ... and the nascent protein must be released from the mRNA and ribosome. Termination of Translation There are three termination codons that ...

Several recently reported structures reveal the details of ribosome architecture and provide new insights into the mechanism of protein synthesis ... density for the N-terminal domain of L11 ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients ...

The large subunit rRNA, in particular, is responsible for the peptidyl transferase reaction, which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery ...

Lots of it. Many ribosomes can be working on a single strand of mRNA at once. Protein synthesis isn't a slow process, either. A protein chain 400 amino acids long can be assembled in 20 seconds!

Cells express their genes by converting the genetic message into protein. This process of protein synthesis occurs in ... the nucleus and travel to the ribosome. After translation, the polypeptide ...