Figure 2: Classical versus electron-based methods for fragmentation of protein and peptide ions in tandem mass spectrometry. Top-down mass spectrometry has made valuable contributions to our ...

“Top-down” is the term used to describe an alternative proteomics approach, where proteins are not enzymatically digested into peptides. They are introduced ... interrogate structures of large ...

Protein sequencing refers to methods for determining the amino acid sequence of proteins (or peptides ... recovering intact proteins for top-down proteomics or partially digested proteins for ...

The flexibility in their structure allows peptides to interact effectively with different receptors in the body, making them essential in signaling pathways. On the other hand, proteins are larger ...

Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on ...

Rather than try to map ... peptides that CLIP indicated could bind to the protein and showed that four could effectively bond to and degrade their target. By destroying the protein, they can slow ...

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular ...

Collagen peptides are made by breaking animal collagen down through hydrolysis. So, while collagen is a complete protein, collagen peptides are fragments of that protein. Whole collagen is ...

"Understanding the structural diversity of nascent peptides formed in the ribosomal tunnel and their role in translational regulation can aid the elimination of bottlenecks in protein synthesis ...