Figure 2: Mitogen-activated protein kinase scaffold proteins in immune ... an important role in facilitating the activation of the cascade, as in the absence of scaffold proteins kinases have ...

These intracellular signaling pathways, also called signal transduction cascades, typically amplify ... For instance, a single second messenger or protein kinase might play a role in more than ...

Blenis, "ras mediates nerve growth factor receptor modulation of three signal- transducing protein kinases: MAP kinase, Raf-1 ... "This paper shows that RAS functions to regulate a cascade of ...

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

Over 20 distinct proteins and protein complexes ... The S phase checkpoint is a kinase signaling cascade that is activated in response to DNA damage or fork stalling during replication stress.

When bound to BMP6, the receptors recruit SMAD proteins and phosphorylation of SMAD1/5/8-SMAD4 complex mobilizes to the nucleus, activating the expression of hepcidin.