The mitogen-activated protein kinase (MAPK) pathway controls the growth ... Of all of the members of the MAPK cascade, it is tempting to speculate that SOS represents one of the most attractive ...

In collaboration with scaffolding proteins that bind the three-kinase cascade together, and as a result of its dual-specificity, MEK1/2 can either function as a single switch through rapid double ...

Cell Growth Discovery: Protein Interactions Of MAP Kinase Signaling Pathway Measured Date: December 30, 2007 Source: Stowers Institute for Medical Research Summary: Scientists have achieved a ...

Different kinases often link together into large cascades or circuits that allow specific ... reports this week how a scaffold protein interacts with a kinase and shows for the first time that ...

When a plant senses an invading pathogen, it activates a molecular signaling cascade ... "Mai1 Protein Acts Between Host Recognition of Pathogen Effectors and Mitogen-Activated Protein Kinase ...

PI3K, phosphoinositide-3-kinase; MEK, mitogen-activated protein kinase kinase ... The first, obvious point of intervention in a signaling cascade is the neutralization of ligands before they can ...

PLK1 initiates the cascade of events by inducing a series of chemical changes ... Reference: Conti D, Verza AE, Pesenti ME, et al. Role of protein kinase PLK1 in the epigenetic maintenance of ...

Blenis, "ras mediates nerve growth factor receptor modulation of three signal- transducing protein kinases: MAP kinase, Raf-1 ... "This paper shows that RAS functions to regulate a cascade of ...