Thus, more studies are needed to understand the detailed mechanism by which propofol exerts its antiarrhythmic effects. Propofol (3 μmol/L) significantly prolonged the rabbit AV conduction ...

Propofol is the most commonly used drug ... Dr. Bentley's team has furthered our understanding of the mechanism of action of a widely used drug that is already impacting human health on a daily ...

The "cross check" with genetically modified GABA receptors in transgenic mice which no longer responded to propofol confirmed that the mechanism of action is the same: the altered receptor also no ...

Propofol is a strong anesthetic that's used for surgery, some medical exams, and for sedation for people on ventilators -- never as a sleep aid. It's given by IV and should only be administered by ...

either by directly repurposing propofol or by designing new, more selective drugs that have the same mechanism of action." Dr. Crina Nimigean, study co-senior author, professor of physiology and ...

Propofol is a drug that binds to GABA receptors in the brain, inhibiting neurons that have those receptors. Other anesthesia drugs act on different types of receptors, and the mechanism for how ...

Trained nurses in most critical care settings often administer propofol safely to patients who are intubated and ventilated. However, some practitioners have been lulled into a false sense of ...

June 18, 2007 -- Clusters of patients in 4 states have experienced chills, fever, and body aches shortly after receiving propofol injectable emulsion ( Diprivan, Abraxis Bioscience, Inc and ...

In hospital operating rooms and intensive care units, propofol is a drug of choice ... Specifically, whether the site of action lies primarily in the thalamus, an egg-shaped structure deep ...

It remains the most widely used anesthetic in U.S. hospitals, but many patients still remember propofol as the drug that killed Michael Jackson. Most are no longer afraid of it, doctors say ...