Such RNA viruses are divided into three classes based on whether their virions package the genome as mRNA-sense (positive-strand) ssRNA, antisense (negative-strand) ssRNA or dsRNA. Other viruses ...

By contrast, some positive-sense single-stranded RNA viruses and some retroviruses such as HIV exhibit high rates of recombination that can exceed the rates of mutation when measured per nucleotide.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense, single-stranded (ss) RNA virus. Upon binding to the angiotensin-converting enzyme 2 (ACE2) receptor ...

SARS-CoV-2 is an enveloped virus with a positive-sense, single-stranded RNA genome of ~30 kb, the authors explained. SARS-CoV-2 belongs to the genus betacoronavirus, together with SARS-CoV and ...

Once engaged, the RNAi mechanism removes the 'sense' strand of the dsRNA leaving a functional 'antisense' single-stranded RNA to bind to the target mRNA and cause degradation. In these studies ...

Research reveals key differences between single- and double-stranded RNA, insights that may prove useful to fields from agriculture to medicine. Messenger RNA, or mRNA, has been in the news ...

The viral proteins of poliovirus are: 3D(pol): an RNA dependent RNA polymerase 2A ... Capsid proteins VP1, VP2, and VP3 all have an eight-stranded β-barrel fold, but have different shaped loops ...

Several years later, Fire and colleagues 1 discovered that double-stranded RNA (dsRNA) mixtures were substantially more potent than sense or antisense single strands at silencing gene expression ...

RNA is similar to DNA but contains uracil instead of thymine (T) and has a single-stranded structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases ...

The RNA that is part of this process exists as a single strand. When a virus attacks the cell's genome, it carries a double-stranded form of RNA that enters the cell. A newly discovered cellular ...

Finally, the team also adapted single-stranded origami technology to RNA, which as a different nucleic acid material offers certain advantages including, for example, even higher production levels ...