Plexiform neurofibromas are tumors that grow along nerves. That’s how they get their name: "neuro" means nerves, and "fibroma" is a type of tumor. These growths have nerve tissue and many ...

ERIN DUNBAR: Plural neurofibromas are the signature abnormal tumor growth found in neurofibromatosis type 1, which is a heritable or familial or genetic condition, and plexiform neurofibromas are ...

Neurofibromatosis type 1-associated plexiform neurofibromas are benign tumors that can grow along nerves anywhere in the body. They may cause complications such as pain, mobility issues, and ...

Plexiform neurofibromas, which affect more the 50% of people with NF1, are tumors that often involve multiple branches of either large or small nerves. They can be located on the surface of the body ...

The study, called KOMET and published in The Lancet, has shown that in 1 in every 5 adults with plexiform neurofibromas treated with selumetinib, there was a significant reduction in the tumor.A ...

Neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN) are manifestations of a rare genetic disorder characterized as irregular, thick and News News CME CME ...

The FDA has approved an oral, small molecule MEK inhibitor for adult and pediatric patients 2 years of age and older with neurofibromatosis type 1 who have symptomatic plexiform neurofibromas not ...

KOMET is an ongoing phase III trial that randomized 145 adults with symptomatic, inoperable NF1-plexiform neurofibromas 1:1 to 28-day cycles of oral selumetinib (25 mg/m² twice daily) or matching ...