The APS, SH2-B and LNK proteins are adapters that activate and modulate receptor tyrosine kinase and JAK/STAT signaling. We now show that a conserved N-terminal domain mediates APS homodimerization.

A new pharmaceutical being developed is offering sufferers of the genetic disease phenylketonuria the hope of being able to eat a normal, protein-rich diet.

Yoshiyuki Tanaka, Makoto Matsuoka, Naoki Yamanoto, Yuko Ohashi, Yuriko Kano-Murakami, Yoshihiro Ozeki, Structure and Characterization of a cDNA Clone for Phenylalanine Ammonia-Lyase from Cut-Injured ...

This release is available in French. Imagine being forced to say no to a child crying for more food at supper. Sadly, Margie Fischer doesn't have to imagine it; that was normal life at her family ...