This module teaches fundamentals of pericyclic reactions using examples of biocatalysis, biomimetic catalysis, and natural product total synthesis. After completion, students should be able to ...

Pericyclic reactions, in which electrons move in concert to rearrange a molecule’s structure, are standard tools for synthetic chemists. But examples of such transformations in nature are fairly ...

The enzyme LepI is found to be capable of catalysing several natural-product pericyclic transformations, including a hetero-Diels–Alder reaction and a retro-Claisen rearrangement. Although ...

Pericyclic reactions are also advantageous for computational work because they are concerted, which means all the bond-breaking and bond-making happens in a single step.

Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such ...

Time-resolved imaging of chemically active valence electron densities is a long-sought goal, as these electrons dictate the course of chemical reactions. However, X-ray scattering is always ...

Researchers used ultrafast electron diffraction to image the structure of the pericyclic minimum, the 'transition state' of electrocyclic reactions. Date: August 2, 2023 ...

Scientists at the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) have illustrated the augmented use of the Artificial Force Induced Reaction (AFIR) method, which predicts pericyclic ...

The material covered includes; molecular orbital theory applied to bonding and reactivity, stereoelectronic and conformational effects, intermolecular interactions, potential energy surfaces, reaction ...

Workshop on Pericyclic Reactions 26 - 27 July 2013, Mumbai, India Introduction A two day lecture series will be conducted on Pericyclic Reactions. The event is a joint venture of Vaze College ...