Peptide-based structures can be designed to yield artificial ... oligonucleotide triple helix and a coiled coil protein domain formation have never been realized for de novo protein design.

The specific secondary structure they observed formed a shape called the 310 helix. Because this work was conducted on peptides, the results lend themselves to a greater understanding of electron ...

Researchers have created the first supermolecule consisting of a DNA helix and peptide ... they managed to change the chirality of the peptide to match DNA’s right-handedness meaning these two ...

Peptide nucleic acid ... all then at the National Institute of Mental Health, created triple helix structures in which a nucleic acid strand attaches itself in the major groove of a duplex ...

Yet, the structure of FusC remained unknown ... Ultimately, they identified a version of FusC with a mutation on helix 11 ...

by analyzing the ratios of 4 types of secondary structures of peptides (?-helix, ?-sheet, ?-turn, and other). They found that the proportion of the ?-sheet conformation was drastically reduced ...

The peptide has 22 residues that curl into an amphipathic α-helix—hydrophilic on one side and hydrophobic ... biophysical techniques revealed that PSMα3 retained its α-helical structure within the ...

Three decades ago, chemists created a synthetic family of DNA-like molecules, peptide nucleic acids (PNAs ... ability to unzip and slip inside a DNA helix, making them ideal tools for gene ...

This structure is essential for giving ... which typically forms a triple helix, and the “cis” form, where the peptide bond ...

Peptides are biomolecules formed when two or ... since after chemical modification the molecule acquires an amyloidal structure, which favors aggregation of molecules, forming plaques like those ...