“All pathogen proteins, like the SARS-CoV-2 spike, have invariant structures critical for their functions, making them good ...

They described their success in Biomacromolecules. Coiled coils, helix-shaped peptides resembling curly ribbons twisted together, are found in nearly 10% of the proteins in many organisms.

“There is great need to revolutionize the current inefficient drug discovery and development process, reducing time, cost and risk.” Pepticom, a pioneer in AI-driven peptide drug discovery and ...

Glucagon-like peptide-1 (GLP-1) receptor agonists are peptide-based therapeutics for treating diabetes and for weight loss.

This target-selective cell-penetrating carrier consists of three sections: a cell-penetrating peptide; a linker that can be joined to a cargo drug; and a targeting moiety peptide. Consequently ...

In FusC, this corresponded to the helix 11 region ... "The ability to generate lasso peptide diversity is important for ...

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.

Antibody-drug conjugates, a well-established antitumor strategy, are used for targeted delivery of cytotoxic drugs through antibodies. As cancer research progresses, other technologies with different ...

Glucagon-like peptide-1 (GLP-1) receptor agonists ... But the industry has only scratched the surface of what these drugs can do. A new range of drugs, currently in the research phase, aim to solve ...