Some drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of these peptides with ureido units.

Oligourea helices have fewer residues per turn, a smaller rise per turn, and a larger diameter than the original peptide alpha-helix." Gilles Guichard, University of Bordeaux.

In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable "disordered" proteins.

Collagen, a protein found in bones and connective tissue, has been found in dinosaur fossils as old as 195 million years.

These peptides are helical and amphipathic (characterized by polar and non-polar side-chains on the surface of the helix). ... Alpha Peptide Foldamers. News-Medical, viewed 09 February 2025, ...

This article was originally published with the title “ Triple Helix: Designing a New Molecule of Life ” in Scientific American Magazine Vol. 299 No. 6 (December 2008) doi:10.1038 ...

Misfolding alpha-synuclein (αS) proteins are considered key players in the development of Parkinson's disease, giving rise to toxic clumps called Lewy bodies that kill off important brain cells ...

Collaboration will strengthen firm’s therapeutic programs as well as consumer-product business. Peptisyntha agreed to manufacture and supply to Helix BioMedix its requirements for certain ...